Ultrastructural alterations within hyperplastic liver nodules induced by ethionine.

نویسندگان

  • L P Merkow
  • S M Epstein
  • M Slifkin
  • E Farber
  • M Pardo
چکیده

Mercaptopurine. L. Lee Bennett, Jr., and Paula W. Allan. 159 Nuclear Pockets Associated with the Nucleolus in Normal and Neoplastic Cells. E. Robert Burns, Bernard L. Soloff, Calvin Hanna, and Donald F. Buxton. 166 The Synergism between Radiation and Estrogen in the Production of Mammary Cancer in the Rat. Albert Segaloff and William S. Maxfield 169 The Effect of L-Asparaginase on Mitotic Activity during N-2-Fluorenylacetamide Hepatocarcino genesis : Subpopulations of Nodular Cells. Frederick F. Becker and Kenneth M. Klein. 174 Ultrastructural Alterations within Hyperplastic Liver Nodules Induced by Ethionine. Leonard P. Merkow, Sheldon M. Epstein, Makoim Slij7cin, Emmanuel Farber, and Matias Pardo. 179 Identification of Three-Line Electron Spin Resonance Signal and Its Relationship to Ascites Tumors. T. Maruyama, N. Kataoka, S. Nagase, H. Nakada, H. Sato, and H. Sasaki. 185 Effects of Chemotherapeutic Agents on Normal Mouse Bone Marrow Grown in Vitro. Clarence H. Brown, III, and Paul P. Carbone. 191 The Effects of 1,3-Bis(2-chloroethyl)-l-nitro sourea on Survival and Cell Progression in Chinese Hamster Cells. S. C. Barranco and R. M. Humphrey. 196 Differences in Tumor Types and Organ Sus ceptibility in BALB/c and RF Mice following Dimethylnitrosamine and Diethylnitrosamine. N. K. Clapp, R. L. Tyndall, and J. A. Otten. 199 Brief Communication: Isolation of Enzymatically Active Nuclei from Epithelial Cells of the Trachea. Joseph M. Smith, Michael B. Sporn, Daniel M. Berkowitz, Tsuyoshi Kakefuda, Emily Callan, and Umberto Saffiotti. 203 Letter to the Editor: Fixation in Hyperosmotic Solutions as a Possible Aid in Visualizing Virions in Tumor Tissue. Richard Siegkr, Iris Hagmann, and Asher D. Kelman. 206 Announcements. 207 Errata.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The ultrastructure of ethionine-induced hyperplastic liver nodules was compared to the adjacent nonnodular liver in the same rat and also to hyperplastic liver nodules induced by 2-fluorenylacetamide. Several reproducible cytostructural

The ultrastructure of ethionine-induced hyperplastic liver nodules was compared to the adjacent nonnodular liver in the same rat and also to hyperplastic liver nodules induced by 2-fluorenylacetamide. Several reproducible cytostructural alterations were noted in ethionine-induced hyperplastic liver nodules of fasted animals but not in adjacent nonnodular liver. This set of alterations was quite...

متن کامل

Functional and structural alterations of liver ergastoplasmic membranes during DL-ethionine hepatocarcinogenesis.

Different functional and structural properties of rat liver microsomes were studied during hepatocarcinogenesis induced by 0.25% DL-ethionine. During the first to fourth months of ethionine feeding, great decreases of cytochrome P-450 content, reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation, and animopyrine demethylase activity occurred. No changes in the reduce...

متن کامل

Membranes during dl-Ethionine Hepatocarcinogenesis Functional and Structural Alterations of Liver Ergastoplasmic

SUMMARY Different functional and structural properties of rat liver microsomes were studied during hepatocarcinogenesis induced by 0.25% m-ethionine. During the first to fourth months of ethionine feeding, great decreases of cytochrome P-450 content, reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation, and aminopyrine demethylase activity occurred. No changes in the...

متن کامل

Cellular analysis of liver carcinogenesis: the induction of large hyperplastic nodules in the liver with 2-fluorenylacetamide or ethionine and some aspects of their morphology and glycogen metabolism.

A dietary regimen is described whereby large hyperplastic nodules can be obtained in over half the rats fed either of the two hepatocarcinogens, ethionine or 2-fluorenylacetamide. The nodules are composed predominantly of hepatocytes which show morphologic and biochemical differences from the surrounding nonhyperplastic liver. The glycogen or its metabolic control are different in the nodule in...

متن کامل

Cellular Analysis of Liver Carcinogenesis: the Induction of Large Hyperplastic Nodules in the Liver with 2-Fluorenylacetamide or Ethionine and Some Aspects of Their Morphology and Glycogen Metabolism1

A dietary regimen is described whereby large hyperplastic nodules can be obtained in over half the rats fed either of the two hepatocarcinogens, ethionine or 2-fluorenylacetamide. The nodules are composed predominantly of hepatocytes which show morphologic and biochemical differences from the surrounding nonhyperplastic liver. The glycogen or its metabolic control are different in the nodule in...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Cancer research

دوره 31 2  شماره 

صفحات  -

تاریخ انتشار 1971